Since 2000, Nashville Zoo has partnered with zoos around the world to develop collaborative breeding programs and field monitoring projects for clouded leopards in Thailand. The resulting Clouded Leopard Consortium is based at the Khao Kheow Open Zoo with assistance from Thailand Zoological Parks Organization (ZPO), Nashville Zoo, Smithsonian's National Zoological Park, Point Defiance Zoo & Aquarium, and the Clouded Leopard Species Survival Program. The Consortium focuses on building a sustainable population in human care of the elusive and threatened cats, and studying wild populations in Southeast Asia.
In the early 2000s, the Consortium focused its research efforts on figuring out how to successfully pair clouded leopards and how to improve cub survival in captivity. The Consortium learned that for successful pairing, male cubs need to be introduced to their future mates by the time the males are six months old. They also learned that hand-rearing cubs from birth is the best way to ensure that clouded leopards are comfortable around humans, which increases their breeding success later in life.